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PGP 2008-2009 | PGP 2009-2010 | PGP 2010-2011
SRP 2009-2010 | SRP 2010-2011
DAP: 2008 | 2009 | 2010 | 2011
PPG: 2008 | 2009 | 2010
SRI in OA 2003-2008 | SRI in IJD 2006-2011 | SRI in BIO 2008-2012
SRID: 2007-2008 | 2006-2007 | 2005-2006 | 2004-2005 | 2003-2005 | 2002-2004
Research Grants Awards
Strategic Research Initiative in Osteoarthritis (OA)
Following the advice of the Network’s Scientific
and Medical Advisory Council to use the skills and expertise
in OA available in Canada strategically, CAN organized an
OA Consensus Conference early in 2002. Network members,
consumers, Canadian and international scientists, and industry
representatives participated and identified the priorities
for future OA research. The priorities include research
on pain and fatigue, the best models, markers and tools
for the evaluation of OA and the most effective models of
OA care. The outcome was the Strategic Research Initiative
(SRI) in OA.
The SRI in OA was funded by a partnership
between CAN and the Canadian Institute
of Health Research’s Institute
of Musculoskeletal Health and Arthritis.
They co-funded three peer-reviewed
grants for a total of $4.4 million
for this research, awarded through
the CIHR NET grant program.
Dr. John Esdaile, of the Arthritis Research Centre of Canada
in Vancouver was awarded $1.5 million to develop tools to
detect OA at an earlier stage than it is currently diagnosed.
This will make early intervention possible, limiting the
disease consequences. The research team includes experts
in diagnostic blood tests for OA, state-of-the-art x-ray
scanners, treatment of OA and measurement of important aspects
of the disease such as limitations on activities, costs,
and psychological consequences.
Dr. Gillian Hawker of Sunnybrook and
Women’s College Health Sciences
Centre in Toronto was awarded $1.4
million to look at the determinants
and consequences of pain and fatigue
in OA using a biopsychosocial approach.
A multidisciplinary team of health
researchers is exploring the relationship
of pain, fatigue, sleep and mental
health in OA in relation to factors
such as coping strategies, family
support and the use of established
treatments. The results will enable
the development of new treatments,
targeted to individuals in the context
of their families and the community
as a whole.
Dr. James Henry, of the University of
Western Ontario in London, was awarded
$1.5 million to look at the molecular
mechanisms of pain and fatigue in
OA in the nervous system and joints.
The research will identify the chemicals
that are altered in and around the
joint at different stages of OA, which
may generate the pain. The project
will also determine the effects of
chemicals released by peripheral nerve
terminals on joint tissues. This work
will help identify new targets to
alleviate pain and prevent tissue
destruction in OA.
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