Pre-Clinical | Clinical | Knowledge Translation and Exchange

Services

Pre-Clinical

CAN's Pre-Clinical Resources facilitate the translation of early stage discoveries into validated targets for clinical testing. Whether you need to evaluate potential anti-arthritis drugs for clinical use or the mechanism of action for drug candidates, the Network's highly qualified experts can develop and implement specific protocols to meet your needs.

Our resources include:

Analytical services

• Histopathology
• Gross morphology
• Immunohistochemistry
• In situ hybridization
• Histomorphology
• SEM and TEM
• Hematology
• Immunology
• Clinical biochemistry
• Molecular genetics
• Cytogenetics
• Biomarker assays
• Expert consultants

In vitro diagnostics and screening systems

A number of proprietary and public domain screening systems are available to measure the impact of treatments on various biological markers of musculoskeletal diseases, including;

• Biomarkers
• Prognostic and predictive indicators
• Imaging
• In vitro screening
• Animal model (non-GLP and GLP), in both proprietary and traditional models

The animal models include:

Rabbit model of osteoarthritis

Sheep model of articular repair

CAN  also provides access to experts in:

• protocol design,
• method validation, and
• data review and analysis.

For more information, contact:

Johnathan Riley
Managing Director
Phone: 416-586-3167

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